Nr3c1tm1.1Jea
Targeted Allele Detail
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Symbol: |
Nr3c1tm1.1Jea |
Name: |
nuclear receptor subfamily 3, group C, member 1; targeted mutation 1.1, Freddy Jeanneteau |
MGI ID: |
MGI:6356399 |
Gene: |
Nr3c1 Location: Chr18:39543598-39652474 bp, - strand Genetic Position: Chr18, 21.09 cM
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Alliance: |
Nr3c1tm1.1Jea page
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Germline Transmission: |
Earliest citation of germline transmission:
J:277414
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: A loxP_2272 site was inserted upstream of exon 2, and an FRT flanked neo cassette, a loxP site, a mutated exon 2 with two serine to alanine mutations (S152A and S284A), a loxP_2272 site and a loxP site were inserted downstream of exon 2. Flp mediated recombination removed the neo cassette.
(J:277414)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nr3c1 Mutation: |
34 strains or lines available
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Original: |
J:277414 Arango-Lievano M, et al., Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors. Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13097-13106 |
All: |
1 reference(s) |
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