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Nr3c1tm1.1Jea
Targeted Allele Detail
Summary
Symbol: Nr3c1tm1.1Jea
Name: nuclear receptor subfamily 3, group C, member 1; targeted mutation 1.1, Freddy Jeanneteau
MGI ID: MGI:6356399
Gene: Nr3c1  Location: Chr18:39543598-39652474 bp, - strand  Genetic Position: Chr18, 21.09 cM
Alliance: Nr3c1tm1.1Jea page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:277414
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP_2272 site was inserted upstream of exon 2, and an FRT flanked neo cassette, a loxP site, a mutated exon 2 with two serine to alanine mutations (S152A and S284A), a loxP_2272 site and a loxP site were inserted downstream of exon 2. Flp mediated recombination removed the neo cassette. (J:277414)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nr3c1 Mutation:  34 strains or lines available
References
Original:  J:277414 Arango-Lievano M, et al., Persistence of learning-induced synapses depends on neurotrophic priming of glucocorticoid receptors. Proc Natl Acad Sci U S A. 2019 Jun 25;116(26):13097-13106
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory