About   Help   FAQ
Transgene Detail
Symbol: Tg(Elf5-cre/ERT2,-GFP)5Rcha
Name: transgene insertion 5, Rumela Chakrabarti
MGI ID: MGI:6343505
Synonyms: Elf5CreERT2-GFP
Transgene: Tg(Elf5-cre/ERT2,-GFP)5Rcha  Location: unknown  
Strain of Origin:  Not Specified
Transgene Type:    Transgenic (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
Mutation detailsA partial coding sequence of exon 2 of Elf5 was replaced with CreERT2-P2A-eGFP-SV40pA-Frt-Neo cassette-Frt by homologous recombination into BAC clone RP23-44A14. The Neo cassette flanked by Frt sites was deleted after FLP-mediated recombination. Six lines were generated and three lines with GFP expression in the mammary glands were kept for the initial screening. Line 2 and 5 showed strong GPF and essentially identical cre activity after tamoxifen induction. Line 2, male founder was selected for the detailed analysis. (J:277468)
 Tissue activity of this recombinase allele
Driver: Elf5     Summary of all recombinase alleles driven by Elf5. Comparative matrix view of recombinase activities

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Original:  J:277468 Singh S, et al., A new Elf5(Cre) (ERT) (2-) (GFP) BAC transgenic mouse model for tracing Elf5 cell lineages in adult tissues. FEBS Lett. 2019 May;593(10):1030-1039
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.15
The Jackson Laboratory