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Pemttm1Jwada
Targeted Allele Detail
Summary
Symbol: Pemttm1Jwada
Name: phosphatidylethanolamine N-methyltransferase; targeted mutation 1, Jun Wada
MGI ID: MGI:6316628
Synonyms: Pemt1tm1
Gene: Pemt  Location: Chr11:59861440-59937315 bp, - strand  Genetic Position: Chr11, 37.81 cM
Alliance: Pemttm1Jwada page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:269081
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 2 of the gene was replaced with a neomycin selection cassette. (J:269081)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pemt Mutation:  15 strains or lines available
References
Original:  J:269081 Watanabe M, et al., Pemt deficiency ameliorates endoplasmic reticulum stress in diabetic nephropathy. PLoS One. 2014;9(3):e92647
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory