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Fosbtm1.1Nes
Targeted Allele Detail
Summary
Symbol: Fosbtm1.1Nes
Name: FBJ osteosarcoma oncogene B; targeted mutation 1.1, Eric J Nestler
MGI ID: MGI:6315234
Gene: Fosb  Location: Chr7:19036621-19043970 bp, - strand  Genetic Position: Chr7, 9.56 cM, cytoband A2-B1
Alliance: Fosbtm1.1Nes page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:276191
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT-flanked neomycin resistnce cassette with a 3' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exons 2 and 3 floxed. (J:276191)
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fosb Mutation:  22 strains or lines available
References
Original:  J:276191 Ohnishi YN, et al., Generation and validation of a floxed FosB mouse line. bioRxiv. 2017;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory