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Pik3ap1M3Btlr
Chemically induced Allele Detail
Nomenclature
Symbol: Pik3ap1M3Btlr
Name: phosphoinositide-3-kinase adaptor protein 1; mutation 3, Bruce Beutler
MGI ID: MGI:6283640
Synonyms: Pintail
Gene: Pik3ap1  Location: Chr19:41272541-41385102 bp, - strand  Genetic Position: Chr19, 34.61 cM, cytoband D1
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsENU-induced T to C transition at base pair 41,376,146 (v38) on chromosome 19, or base pair 8,925 in the GenBank genomic region NC_000085 encoding Pik3ap1. The mutation corresponds to residue 303 in the NM_031376.3 mRNA sequence in exon 2 of 17 total exons. The mutation results in a tyrosine to histidine substitution at position 45 (Y45H) in the B cell adaptor protein (BCAP) protein. (J:272019)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pik3ap1 Mutation:  33 strains or lines available
Notes
https://mutagenetix.utsouthwestern.edu/phenotypic/phenotypic_rec.cfm?pk=3628
References
Original:  J:272019 Zhong X, et al., Mutagenetix entry for Pintail. MGI Direct Data Submission. 2019;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/19/2020
MGI 6.15
The Jackson Laboratory