Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Pik3ap1M3Btlr
Name:	phosphoinositide-3-kinase adaptor protein 1; mutation 3, Bruce Beutler
MGI ID:	MGI:6283640
Synonyms:	Pintail
Gene:	Pik3ap1  Location: Chr19:41260980-41373541 bp, - strand  Genetic Position: Chr19, 34.61 cM, cytoband D1
Alliance:	Pik3ap1M3Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) (Not Specified) Mutation:    Single point mutation   Mutation details: ENU-induced T to C transition at base pair 41,376,146 (v38) on chromosome 19, or base pair 8,925 in the GenBank genomic region NC_000085 encoding Pik3ap1. The mutation corresponds to residue 303 in the NM_031376.3 mRNA sequence in exon 2 of 17 total exons. The mutation results in a tyrosine to histidine substitution at position 45 (Y45H) in the B cell adaptor protein (BCAP) protein. (J:272019) Inheritance:    Dominant

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pik3ap1 Mutation:	50 strains or lines available

Original:	J:272019 Zhong X, et al., Mutagenetix entry for Pintail. MGI Direct Data Submission. 2019;
All:	1 reference(s)