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Sox4tm1.1Blas
Targeted Allele Detail
Summary
Symbol: Sox4tm1.1Blas
Name: SRY (sex determining region Y)-box 4; targeted mutation 1.1, Maria A Blasco
MGI ID: MGI:6281590
Synonyms: Sox4KI, Sox4loxp
Gene: Sox4  Location: Chr13:29132902-29137682 bp, - strand  Genetic Position: Chr13, 12.87 cM, cytoband A3-A5
Alliance: Sox4tm1.1Blas page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:266021
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Hypomorph, Reporter)
Mutation:    Insertion
 
Mutation detailsA loxP site, 5' UTR, exon 1, IRES sequence, GFP/luciferase reporter gene, FRT-flanked neomycin resistance cassette and loxP site. Flp-mediated recombination removed the selection cassette. (J:266021)
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Sox4 Mutation:  20 strains or lines available
References
Original:  J:266021 Foronda M, et al., Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation. Cell Rep. 2014 Jul 24;8(2):487-500
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory