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Relatm1.1Bras
Targeted Allele Detail
Summary
Symbol: Relatm1.1Bras
Name: v-rel reticuloendotheliosis viral oncogene homolog A (avian); targeted mutation 1.1, Allan R Brasier
MGI ID: MGI:6281191
Synonyms: RelACKO
Gene: Rela  Location: Chr19:5687511-5698158 bp, + strand  Genetic Position: Chr19, 4.34 cM, cytoband B1-3
Alliance: Relatm1.1Bras page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:235787
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  (129 x C57BL/6)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site and frt-flanked neomycin selection cassette were inserted about 0.6-kb upstream of exon 5. A second loxP site was inserted about 240-bp downstream of exon 8. Flp-mediated recombination removed the neomycin cassette, leaving exons 5-8 floxed. (J:235787)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rela Mutation:  24 strains or lines available
References
Original:  J:235787 Ijaz T, et al., Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles. BMC Dev Biol. 2016 Sep 23;16(1):32
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory