Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ebf1M4Btlr
Name:	early B cell factor 1; mutation 4, Bruce Beutler
MGI ID:	MGI:6268783
Synonyms:	Catastrophic
Gene:	Ebf1  Location: Chr11:44508144-44898918 bp, + strand  Genetic Position: Chr11, 26.45 cM
Alliance:	Ebf1M4Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) (Not Specified) Mutation:    Single point mutation   Mutation details: ENU-induced T to A transversion at base pair 44,883,885 (v38) on chromosome 11, or base pair 265,786 in the GenBank genomic region NC_000077. The mutation corresponds to residue 787 in the mRNA sequence NM_001290709 within exon 8 of 16 total exons. The mutation results in an asparagine to lysine substitution at position 236 (N236K) in the EBF1 protein. (J:267560) Inheritance:    Dominant

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ebf1 Mutation:	73 strains or lines available

Original:	J:267560 Choi JH, et al., Mutagenetix entry for Catastrophic. MGI Direct Data Submission. 2018;
All:	1 reference(s)