Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mioxtm1Ysk
Name:	myo-inositol oxygenase; targeted mutation 1, Yashpal S Kanwar
MGI ID:	MGI:6267379
Gene:	Miox  Location: Chr15:89218676-89221210 bp, + strand  Genetic Position: Chr15, 44.82 cM
Alliance:	Mioxtm1Ysk page

Germline Transmission:	Earliest citation of germline transmission: J:266834
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S/SvEv

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 10. (J:266834)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Miox Mutation:	37 strains or lines available

Original:	J:266834 Dutta RK, et al., Beneficial Effects of Myo-Inositol Oxygenase Deficiency in Cisplatin-Induced AKI. J Am Soc Nephrol. 2017 May;28(5):1421-1436
All:	6 reference(s)