Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Irf4em1Holi
Name:	interferon regulatory factor 4; endonuclease-mediated mutation 1, Hongliang Li
MGI ID:	MGI:6258425
Gene:	Irf4  Location: Chr13:30933209-30950959 bp, + strand  Genetic Position: Chr13, 13.28 cM, cytoband A3.3
Alliance:	Irf4em1Holi page

Strain of Origin:

Not Specified

Allele Type:    Endonuclease-mediated (Null/knockout) Mutation:    Intragenic deletion   Mutation details: CRISPR/Cas9 technology resulted in a 34 bp deletion in exon 2 generating a knock-out allele. Western blot analysis confirmed absence of protein in homozygotes. (J:266946)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Irf4 Mutation:	27 strains or lines available

Original:	J:266946 Cheng WL, et al., Interferon Regulatory Factor 4 Inhibits Neointima Formation by Engaging Kruppel-Like Factor 4 Signaling. Circulation. 2017 Oct 10;136(15):1412-1433
All:	1 reference(s)