Has3tm1.1(HAS3)Geno
Targeted Allele Detail
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Symbol: |
Has3tm1.1(HAS3)Geno |
Name: |
hyaluronan synthase 3; targeted mutation 1.1, Genoway |
MGI ID: |
MGI:6201738 |
Gene: |
Has3 Location: Chr8:107596874-107609534 bp, + strand Genetic Position: Chr8, 53.28 cM
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Alliance: |
Has3tm1.1(HAS3)Geno page
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Germline Transmission: |
Earliest citation of germline transmission:
J:246850
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence, Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Has3tm1.1(HAS3)Geno expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
HAS3 (3038) |
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Mutation details: An FRT flanked neo cassette and floxed human HAS3 cDNA replaced exon 2 via homologous recombination. Flp meditated recombination removed the neo cassette.
(J:246850)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Has3 Mutation: |
16 strains or lines available
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Original: |
J:246850 Kiene LS, et al., Deletion of Hyaluronan Synthase 3 Inhibits Neointimal Hyperplasia in Mice. Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):e9-16 |
All: |
1 reference(s) |
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