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Has3tm1.1(HAS3)Geno
Targeted Allele Detail
Summary
Symbol: Has3tm1.1(HAS3)Geno
Name: hyaluronan synthase 3; targeted mutation 1.1, Genoway
MGI ID: MGI:6201738
Gene: Has3  Location: Chr8:107596874-107609534 bp, + strand  Genetic Position: Chr8, 53.28 cM
Alliance: Has3tm1.1(HAS3)Geno page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:246850
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence, Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Has3tm1.1(HAS3)Geno expresses 1 gene
 
Mutation detailsAn FRT flanked neo cassette and floxed human HAS3 cDNA replaced exon 2 via homologous recombination. Flp meditated recombination removed the neo cassette. (J:246850)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Has3 Mutation:  16 strains or lines available
References
Original:  J:246850 Kiene LS, et al., Deletion of Hyaluronan Synthase 3 Inhibits Neointimal Hyperplasia in Mice. Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):e9-16
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory