Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ikzf1m3Btlr
Name:	IKAROS family zinc finger 1; mutation 3, Bruce Beutler
MGI ID:	MGI:6200327
Synonyms:	herrscher
Gene:	Ikzf1  Location: Chr11:11634980-11722926 bp, + strand  Genetic Position: Chr11, 7.02 cM
Alliance:	Ikzf1m3Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) (Not Specified) Mutation:    Single point mutation   Mutation details: ENU-induced C to T transition at base pair 11,768,961(v38) on chromosome 11, or base pair 83,993 in the GenBank genomic region NC_000077 encoding Ikzf1. The mutation corresponds to residue 1,486 in the mRNA sequence NM_001025597 within exon 8 of 8 total exons. The mutation results in substitution of glutamine 310 for a premature stop codon (Q310*) in variant 1 of the IKZF1 protein. (J:265251) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ikzf1 Mutation:	30 strains or lines available

Original:	J:265251 Zhong X, et al., Mutagenetix entry for herrscher. MGI Direct Data Submission. 2018;
All:	1 reference(s)