Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ikzf1m1Btlr
Name:	IKAROS family zinc finger 1; mutation 1, Bruce Beutler
MGI ID:	MGI:6200316
Synonyms:	star_lord
Gene:	Ikzf1  Location: Chr11:11634980-11722926 bp, + strand  Genetic Position: Chr11, 7.02 cM
Alliance:	Ikzf1m1Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) (Not Specified) Mutation:    Single point mutation   Mutation details: ENU-induced T to A transversion at base pair 11,769,448 (v38) on chromosome 11, or base pair 84,479 in the GenBank genomic region NC_000077 encoding Ikzf1. The mutation corresponds to residue 1,972 in the mRNA sequence NM_001025597 within exon 8 of 8 total exons. The mutation results in a methionine to lysine substitution at amino acid 472 (M472K) in variant 1 of the IKZF1 protein. (J:265249) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ikzf1 Mutation:	30 strains or lines available

Original:	J:265249 Teixeira S, et al., Mutagenetix entry for star_lord. MGI Direct Data Submission. 2018;
All:	1 reference(s)