Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pax5m4Btlr
Name:	paired box 5; mutation 4, Bruce Beutler
MGI ID:	MGI:6199943
Synonyms:	k2
Gene:	Pax5  Location: Chr4:44524757-44710487 bp, - strand  Genetic Position: Chr4, 23.55 cM
Alliance:	Pax5m4Btlr page

Strain of Origin:	C57BL/6J
Project Collection:	Beutler Mutagenetix

Allele Type:    Chemically induced (ENU) (Not Specified) Mutation:    Single point mutation   Mutation details: ENU-induced A to G transition at base pair 44,697,630 (v38) on chromosome 4, or base pair 12,811 in the GenBank genomic region NC_000070. The mutation corresponds to residue 390 in the mRNA sequence NM_008782 within exon 2 of 10 total exons. The mutation results in an aspartic acid to glycine substitution at position 35 (D35G) in the canonical variant of the PAX5 protein. (J:265140) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pax5 Mutation:	35 strains or lines available

Original:	J:265140 Zhong X, et al., Mutagenetix entry for k2. MGI Direct Data Submission. 2018;
All:	1 reference(s)