Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Cebpbtm1.1Elgaz
Name:	CCAAT/enhancer binding protein beta; targeted mutation 1.1, Mohamed Elgazzar
MGI ID:	MGI:6195224
Synonyms:	Cebpbflox
Gene:	Cebpb  Location: Chr2:167530835-167532338 bp, + strand  Genetic Position: Chr2, 87.58 cM
Alliance:	Cebpbtm1.1Elgaz page

Germline Transmission:	Earliest citation of germline transmission: J:247885
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	BALB/cJ

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: The targeting vector contains a loxP site flanked PGK-Neo selection cassette inserted 228 bp downstream of the Cebpb polyadenylation site, and another loxP site inserted 227 bp upstream of the Cebpb initiation start site. Cre-mediated recombination removed the floxed neo cassette. (J:247885)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cebpb Mutation:	23 strains or lines available

Original:	J:247885 McPeak MB, et al., Frontline Science: Myeloid cell-specific deletion of Cebpb decreases sepsis-induced immunosuppression in mice. J Leukoc Biol. 2017 Aug;102(2):191-200
All:	2 reference(s)