Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Rr123em1Kslr
Name:	regulatory region 123; endonuclease-mediated mutation 1, Stephan Kissler
MGI ID:	MGI:6194663
Synonyms:	CNS1 KO, Foxp3em1Kslr
Gene:	Rr123  Location: unknown  Genetic Position: ChrX, Syntenic
Alliance:	Rr123em1Kslr page

Strain of Origin:

NOD

Allele Type:    Endonuclease-mediated (Modified regulatory region) Mutation:    Intragenic deletion   Mutation details: CRISPR-targeting removed the enhancer CNS1 (Conserved non-coding sequence 1) located in the promoter. (J:263779)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rr123 Mutation:	0 strains or lines available

Original:	J:263779 Schuster C, et al., Peripherally induced regulatory T cells contribute to the control of autoimmune diabetes in the NOD mouse model. Eur J Immunol. 2018 Jul;48(7):1211-1216
All:	1 reference(s)