Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Grin3atm1Nnk
Name:	glutamate receptor ionotropic, NMDA3A; targeted mutation 1, Nobuki Nakanishi
MGI ID:	MGI:2387963
Synonyms:	NR3A-
Gene:	Grin3a  Location: Chr4:49661611-49845744 bp, - strand  Genetic Position: Chr4, 26.72 cM
Alliance:	Grin3atm1Nnk page

Germline Transmission:	Earliest citation of germline transmission: J:66481
Parent Cell Line:	C1 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: The region encoding the N-terminal 118 amino acids (including the translation initation codon) was replaced with a PGK-neo cassette via homologous recombination. Homozygous mutant animals lacked gene expression as demonstrated by Northern and Western blot analysis of brain samples. (J:66481)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Grin3a Mutation:	50 strains or lines available

Original:	J:66481 Das S, et al., Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A. Nature. 1998 May 28;393(6683):377-81
All:	23 reference(s)