Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gcatem1Jiha
Name:	glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase); endonuclease-mediated mutation 1, Jun-Ichi Hayashi
MGI ID:	MGI:6150910
Synonyms:	Gcat m
Gene:	Gcat  Location: Chr15:78915074-78926731 bp, + strand  Genetic Position: Chr15, 37.7 cM
Alliance:	Gcatem1Jiha page

Strain of Origin:

C57BL/6JJcl

Allele Type:    Endonuclease-mediated (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: CRISPR mutagenesis induced a 7 bp insertion and a 39 bp deletion in the gene. The encoded protein was not detectable in livers of 5-month-old homozygous mice. (J:259713)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

4 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gcat Mutation:	19 strains or lines available

Original:	J:259713 Tani H, et al., Mice deficient in the Shmt2 gene have mitochondrial respiration defects and are embryonic lethal. Sci Rep. 2018 Jan 11;8(1):425
All:	1 reference(s)