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Targeted Allele Detail
Symbol: Pou3f2tm2.1(pou3f2)Lmame
Name: POU domain, class 3, transcription factor 2; targeted mutation 2.1, Shintaroh Ueda
MGI ID: MGI:6149147
Synonyms: Pou3f2tm2.1(xPou3f2)Lmame, tro
Gene: Pou3f2  Location: Chr4:22482780-22488366 bp, - strand  Genetic Position: Chr4, 9.73 cM
Germline Transmission:  Earliest citation of germline transmission: J:259381
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Inserted expressed sequence, Null/knockout)
Mutations:    Insertion, Intragenic deletion
Pou3f2tm2.1(pou3f2)Lmame expresses 1 gene
Mutation detailsThe coding region was replaced with a genomic region containing the gene encoding Xenopus pou3f2. The Xenopus gene lacks the glycine, glutamine, and proline repeats, found in the mammalian orthologs. A loxP-flanked neomycin selection cassette was removed in vitro in ES cells prior to the production of mice. (J:259381)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou3f2 Mutation:  3 strains or lines available
Original:  J:259381 Nasu M, et al., Mammalian-specific sequences in pou3f2 contribute to maternal behavior. Genome Biol Evol. 2014 Apr 7;6(5):1145-56
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory