Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Pou3f2tm2.1(pou3f2)Lmame
Name:	POU domain, class 3, transcription factor 2; targeted mutation 2.1, Shintaroh Ueda
MGI ID:	MGI:6149147
Synonyms:	Pou3f2tm2.1(xPou3f2)Lmame, tro
Gene:	Pou3f2  Location: Chr4:22482780-22488366 bp, - strand  Genetic Position: Chr4, 9.73 cM
Alliance:	Pou3f2tm2.1(pou3f2)Lmame page

Germline Transmission:	Earliest citation of germline transmission: J:259381
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Inserted expressed sequence, Null/knockout) Mutations:    Insertion, Intragenic deletion   Pou3f2tm2.1(pou3f2)Lmame expresses 1 gene Knock-in expresses: Organism Expressed Gene Note frog, western clawed pou3f2 (100486226)   Mutation details: The coding region was replaced with a genomic region containing the gene encoding Xenopus pou3f2. The Xenopus gene lacks the glycine, glutamine, and proline repeats, found in the mammalian orthologs. A loxP-flanked neomycin selection cassette was removed in vitro in ES cells prior to the production of mice. (J:259381)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pou3f2 Mutation:	19 strains or lines available

Original:	J:259381 Nasu M, et al., Mammalian-specific sequences in pou3f2 contribute to maternal behavior. Genome Biol Evol. 2014 Apr 7;6(5):1145-56
All:	1 reference(s)