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Gt(ROSA)26Sortm1(Foxf1)Psta
Targeted Allele Detail
Nomenclature
Symbol: Gt(ROSA)26Sortm1(Foxf1)Psta
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Pawel Stankiewicz
MGI ID: MGI:6118052
Synonyms: R26-LSL-Foxf1
Gene: Gt(ROSA)26Sor  Location: Chr6:113044389-113054205 bp, - strand  Genetic Position: Chr6, 52.73 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:237109
Parent Cell Line:  JM8A3 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Mutation
description
Allele Type:    Targeted (Conditional ready, Inserted expressed sequence)
Mutation:    Insertion
 
Gt(ROSA)26Sortm1(Foxf1)Psta expresses 1 gene
 
Mutation detailsThe targeting construct inserted into the locus a floxed PGK-neo STOP cassette (LSL) followed by the Foxf1 cDNA. Upon Cre-induced recombination, the STOP cassette is excised and the cDNA is expressed. (J:237109)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:  741 strains or lines available
References
Original:  J:237109 Dharmadhikari AV, et al., Lethal lung hypoplasia and vascular defects in mice with conditional Foxf1 overexpression. Biol Open. 2016 Nov 15;5(11):1595-1606
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory