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Rfx1tm1.1Wrth
Targeted Allele Detail
Summary
Symbol: Rfx1tm1.1Wrth
Name: regulatory factor X, 1 (influences HLA class II expression); targeted mutation 1.1, Walter Reith
MGI ID: MGI:5907528
Synonyms: Rfx1flox
Gene: Rfx1  Location: Chr8:84793463-84823621 bp, + strand  Genetic Position: Chr8, 40.28 cM
Alliance: Rfx1tm1.1Wrth page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:227631
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 10 was flanked with loxP sites and an FRT flanked neo cassette was inserted in intron 10 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:227631)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rfx1 Mutation:  46 strains or lines available
References
Original:  J:227631 Elkon R, et al., RFX transcription factors are essential for hearing in mice. Nat Commun. 2015;6:8549
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory