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Endonuclease-mediated Allele Detail
Symbol: Aireem2Jrt
Name: autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy); endonuclease-mediated mutation 2, Janet Rossant
MGI ID: MGI:5907266
Synonyms: AireFL, AireFlox, Airetm2Jrt
Gene: Aire  Location: Chr10:78030022-78043610 bp, - strand  Genetic Position: Chr10, 39.72 cM
Strain of Origin:  CD-1
Allele Type:    Endonuclease-mediated (Conditional ready, No functional change)
Mutation:    Insertion
    CRISPR/Cas technology inserted loxP sites flanking exons 8 and 9. (J:242967)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aire Mutation:  33 strains or lines available
Original:  J:242967 Gu B, et al., AIRE is a critical spindle-associated protein in embryonic stem cells. Elife. 2017 Jul 25;6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory