Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Aireem2Jrt
Name:	autoimmune regulator; endonuclease-mediated mutation 2, Janet Rossant
MGI ID:	MGI:5907266
Synonyms:	AireFL, AireFlox, Airetm2Jrt
Gene:	Aire  Location: Chr10:77865856-77879444 bp, - strand  Genetic Position: Chr10, 39.72 cM
Alliance:	Aireem2Jrt page

Strain of Origin:

CD-1

Allele Type:    Endonuclease-mediated (Conditional ready, No functional change) Mutation:    Insertion     CRISPR/Cas technology inserted loxP sites flanking exons 8 and 9. (J:242967)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aire Mutation:	52 strains or lines available

Original:	J:242967 Gu B, et al., AIRE is a critical spindle-associated protein in embryonic stem cells. Elife. 2017 Jul 25;6:e28131
All:	1 reference(s)