About   Help   FAQ
Foxf1tm1.1Vvk
Targeted Allele Detail
Nomenclature
Symbol: Foxf1tm1.1Vvk
Name: forkhead box F1; targeted mutation 1.1, Vladimir V Kalinichenko
MGI ID: MGI:5902536
Synonyms: Foxf1fl
Gene: Foxf1  Location: Chr8:121811125-121814883 bp, + strand  Genetic Position: Chr8, 70.31 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:240455
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6 x 129
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted into the promotor region upstream of exon 1 and a second loxP site and a neomycin resistance gene cassette into intron 1. The neo cassette was deleted through subsequent flp-mediated recombination, leaving a conditional-ready allele with a floxed exon 1. (J:240455)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxf1 Mutation:  6 strains or lines available
References
Original:  J:240455 Ren X, et al., FOXF1 transcription factor is required for formation of embryonic vasculature by regulating VEGF signaling in endothelial cells. Circ Res. 2014 Sep 26;115(8):709-20
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
11/23/2021
MGI 6.17
The Jackson Laboratory