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Targeted Allele Detail
Symbol: Foxf1tm1.1Vvk
Name: forkhead box F1; targeted mutation 1.1, Vladimir V Kalinichenko
MGI ID: MGI:5902536
Synonyms: Foxf1fl
Gene: Foxf1  Location: Chr8:121811125-121814883 bp, + strand  Genetic Position: Chr8, 70.31 cM, cytoband E1
Germline Transmission:  Earliest citation of germline transmission: J:240455
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6 x 129
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
Mutation detailsA loxP site was inserted into the promotor region upstream of exon 1 and a second loxP site and a neomycin resistance gene cassette into intron 1. The neo cassette was deleted through subsequent flp-mediated recombination, leaving a conditional-ready allele with a floxed exon 1. (J:240455)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxf1 Mutation:  6 strains or lines available
Original:  J:240455 Ren X, et al., FOXF1 transcription factor is required for formation of embryonic vasculature by regulating VEGF signaling in endothelial cells. Circ Res. 2014 Sep 26;115(8):709-20
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.17
The Jackson Laboratory