Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Foxf1tm1.1Vvk
Name:	forkhead box F1; targeted mutation 1.1, Vladimir V Kalinichenko
MGI ID:	MGI:5902536
Synonyms:	Foxf1fl
Gene:	Foxf1  Location: Chr8:121811125-121814883 bp, + strand  Genetic Position: Chr8, 70.31 cM, cytoband E1
Alliance:	Foxf1tm1.1Vvk page

Germline Transmission:	Earliest citation of germline transmission: J:240455
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6 x 129

Allele Type:    Targeted (Conditional ready) Mutation:    Insertion   Mutation details: A loxP site was inserted into the promotor region upstream of exon 1 and a second loxP site and a neomycin resistance gene cassette into intron 1. The neo cassette was deleted through subsequent flp-mediated recombination, leaving a conditional-ready allele with a floxed exon 1. (J:240455)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxf1 Mutation:	13 strains or lines available

Original:	J:240455 Ren X, et al., FOXF1 transcription factor is required for formation of embryonic vasculature by regulating VEGF signaling in endothelial cells. Circ Res. 2014 Sep 26;115(8):709-20
All:	7 reference(s)