About   Help   FAQ
Bhlha15tm5Skz
Targeted Allele Detail
Summary
Symbol: Bhlha15tm5Skz
Name: basic helix-loop-helix family, member a15; targeted mutation 5, Stephen F Konieczny
MGI ID: MGI:5882090
Synonyms: Mist1flox
Gene: Bhlha15  Location: Chr5:144127104-144131259 bp, + strand  Genetic Position: Chr5, 83.05 cM, cytoband G2-G3
Alliance: Bhlha15tm5Skz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:239586
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsExon 2 was flanked by loxP sites and sequence for a biotin tag was inserted at the 5' end of the gene and MYC tag sequence at the 3' end. This creates a conditional-ready allele with exon 2 floxed and codes for a peptide with an N-terminal biotin tag and C-terminal MYC tag. (J:239586)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bhlha15 Mutation:  15 strains or lines available
References
Original:  J:239586 Lo HG, et al., A single transcription factor is sufficient to induce and maintain secretory cell architecture. Genes Dev. 2017 Jan 15;31(2):154-171
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory