Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Hoxa5tm1.1Dmwe
Name:	homeobox A5; targeted mutation 1.1, Deneen Wellik
MGI ID:	MGI:5827550
Synonyms:	Hoxa5Flox
Gene:	Hoxa5  Location: Chr6:52178768-52181437 bp, - strand  Genetic Position: Chr6, 25.4 cM
Alliance:	Hoxa5tm1.1Dmwe page

Germline Transmission:	Earliest citation of germline transmission: J:232894
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette and left exon 2 floxed. (J:232894)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa5 Mutation:	27 strains or lines available

Original:	J:232894 Hrycaj SM, et al., Hox5 Genes Regulate the Wnt2/2b-Bmp4-Signaling Axis during Lung Development. Cell Rep. 2015 Aug 11;12(6):903-12
All:	1 reference(s)