Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Slc6a8tm1.2Lbar
Name:	solute carrier family 6 (neurotransmitter transporter, creatine), member 8; targeted mutation 1.2, Laura Baroncelli
MGI ID:	MGI:5825019
Synonyms:	CrT-
Gene:	Slc6a8  Location: ChrX:72716756-72726108 bp, + strand  Genetic Position: ChrX, 37.38 cM
Alliance:	Slc6a8tm1.2Lbar page

Germline Transmission:	Earliest citation of germline transmission: J:232606
Parent Cell Line:	A8 (ES Cell)
Strain of Origin:	(C57BL/6 x 129P2/OlaHsd)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A reporter knock-out allele was generated via cre-mediated recombination which removed the floxed exons 5-7 and left an FRT site, followed by lacZ sequence and a loxP site upstream of the deleted exons. (J:232606)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc6a8 Mutation:	10 strains or lines available

Original:	J:232606 Baroncelli L, et al., A novel mouse model of creatine transporter deficiency. F1000Res. 2014;3:228
All:	7 reference(s)