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Pax5em1Cgmn
Endonuclease-mediated Allele Detail
Summary
Symbol: Pax5em1Cgmn
Name: paired box 5; endonuclease-mediated mutation 1, Charles G Mullighan
MGI ID: MGI:5818803
Synonyms: Pax5-P80R, Pax5p.Pro80Arg
Gene: Pax5  Location: Chr4:44524757-44710487 bp, - strand  Genetic Position: Chr4, 23.55 cM
Alliance: Pax5em1Cgmn page
Mutation
origin
Strain of Origin:  C57BL/6NJ
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Undefined
    CRISPR-targeting induced the amino acid substitution of arginine for proline at position 80. (J:270049)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pax5 Mutation:  35 strains or lines available
References
Original:  J:270049 Gu Z, et al., PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia. Nat Genet. 2019 Feb;51(2):296-307
All:  1 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory