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Nkx6-1m1Mhda
Chemically induced Allele Detail
Summary
Symbol: Nkx6-1m1Mhda
Name: NK6 homeobox 1; mutation 1, Martin Hrabe de Angelis
MGI ID: MGI:5818754
Synonyms: Nkx6D325NMhda
Gene: Nkx6-1  Location: Chr5:101807050-101812577 bp, - strand  Genetic Position: Chr5, 48.84 cM
Alliance: Nkx6-1m1Mhda page
Mutation
origin
Strain of Origin:  C3HeB/FeJ
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsThe molecular lesion is a C-to-T missense mutation (973C-T) in codon 325 in exon 3. This is predicted to alter amino acid 325 from an aspartic acid to an asparagine (D325N) in the encoded protein. (J:237905)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nkx6-1 Mutation:  4 strains or lines available
References
Original:  J:237905 Sabrautzki S, et al., Alleles produced by the Munich ENU mutagenesis project. MGI Direct Data Submission. 2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory