Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Inpp5jtm1.1Cmit
Name:	inositol polyphosphate 5-phosphatase J; targeted mutation 1.1, Christina A Mitchell
MGI ID:	MGI:5789330
Synonyms:	Pipp-
Gene:	Inpp5j  Location: Chr11:3444375-3454821 bp, - strand  Genetic Position: Chr11, 2.45 cM
Alliance:	Inpp5jtm1.1Cmit page

Germline Transmission:	Earliest citation of germline transmission: J:224914
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	C57BL/6

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: Exon 2 and a neomycin selection cassette was deleted via Cre-mediated recombination of flanking loxP sites. Quantitative RT-PCR analysis confirmed the absence of mRNA expression in homozygous mutant brains. (J:224914)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Inpp5j Mutation:	41 strains or lines available

Original:	J:224914 Ooms LM, et al., The Inositol Polyphosphate 5-Phosphatase PIPP Regulates AKT1-Dependent Breast Cancer Growth and Metastasis. Cancer Cell. 2015 Aug 10;28(2):155-69
All:	1 reference(s)