Nfat5tm1.1Chku
Targeted Allele Detail
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Symbol: |
Nfat5tm1.1Chku |
Name: |
nuclear factor of activated T cells 5; targeted mutation 1.1, Christoph Kuper |
MGI ID: |
MGI:5784719 |
Synonyms: |
NFAT5flx |
Gene: |
Nfat5 Location: Chr8:108020102-108106149 bp, + strand Genetic Position: Chr8, 53.93 cM, cytoband D2
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Alliance: |
Nfat5tm1.1Chku page
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Germline Transmission: |
Earliest citation of germline transmission:
J:232839
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Parent Cell Line: |
iTL BA1 (ES Cell)
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Strain of Origin: |
(C57BL/6NTac x 129S6/SvEvTac)F1
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: The construct targeting exon 4 consisted of a loxP site in intron 3 and a neo cassette (FRT-flanked pGK-gb2 Neo and a loxP site) in intron 4. Flp-mediated recombination removed the neo cassette, leaving a single FRT site and the loxP site behind. Exon 4 is floxed.
(J:232839)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nfat5 Mutation: |
62 strains or lines available
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Original: |
J:232839 Kuper C, et al., Generation of a conditional knockout allele for the NFAT5 gene in mice. Front Physiol. 2014;5:507 |
All: |
10 reference(s) |
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