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Nfat5tm1.1Chku
Targeted Allele Detail
Summary
Symbol: Nfat5tm1.1Chku
Name: nuclear factor of activated T cells 5; targeted mutation 1.1, Christoph Kuper
MGI ID: MGI:5784719
Synonyms: NFAT5flx
Gene: Nfat5  Location: Chr8:108020102-108106149 bp, + strand  Genetic Position: Chr8, 53.93 cM, cytoband D2
Alliance: Nfat5tm1.1Chku page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:232839
Parent Cell Line:  iTL BA1 (ES Cell)
Strain of Origin:  (C57BL/6NTac x 129S6/SvEvTac)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsThe construct targeting exon 4 consisted of a loxP site in intron 3 and a neo cassette (FRT-flanked pGK-gb2 Neo and a loxP site) in intron 4. Flp-mediated recombination removed the neo cassette, leaving a single FRT site and the loxP site behind. Exon 4 is floxed. (J:232839)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfat5 Mutation:  62 strains or lines available
References
Original:  J:232839 Kuper C, et al., Generation of a conditional knockout allele for the NFAT5 gene in mice. Front Physiol. 2014;5:507
All:  10 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory