Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Pik3c2gtm1Ehi
Name:	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; targeted mutation 1, Emilio Hirsch
MGI ID:	MGI:5779504
Synonyms:	Pik3c2glacZ
Gene:	Pik3c2g  Location: Chr6:139591070-139915010 bp, + strand  Genetic Position: Chr6, 69.7 cM
Alliance:	Pik3c2gtm1Ehi page

Germline Transmission:	Earliest citation of germline transmission: J:223018
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Reporter) Mutations:    Insertion, Intragenic deletion   Mutation details: A lacZ and floxed neomycin resistance cassette replaced most of exon 1. RT-PCR confirmed the absence of protein expression in the liver. (J:223018)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pik3c2g Mutation:	77 strains or lines available

Original:	J:223018 Braccini L, et al., PI3K-C2gamma is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nat Commun. 2015;6:7400
All:	1 reference(s)