Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Cybatm1Dgh
Name:	cytochrome b-245, alpha polypeptide; targeted mutation 1, David G Harrison
MGI ID:	MGI:5775909
Synonyms:	p22phox/flox
Gene:	Cyba  Location: Chr8:123151515-123159669 bp, - strand  Genetic Position: Chr8, 71.04 cM, cytoband E1
Alliance:	Cybatm1Dgh page

Germline Transmission:	Earliest citation of germline transmission: J:231269
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Conditional ready, No functional change) Mutation:    Insertion   Mutation details: A floxed neomycin resistance cassette was inserted 7.1 kb upstream of the transcription start site. An additional loxP site was inserted in intron 1. (J:231269)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

6 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cyba Mutation:	17 strains or lines available

Original:	J:231269 Lob HE, et al., Role of the NADPH oxidases in the subfornical organ in angiotensin II-induced hypertension. Hypertension. 2013 Feb;61(2):382-7
All:	3 reference(s)