Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	E4f1tm1.2Melo
Name:	E4F transcription factor 1; targeted mutation 1.1, Sylvain Meloche
MGI ID:	MGI:5763666
Synonyms:	E4f1delta
Gene:	E4f1  Location: Chr17:24662752-24674366 bp, - strand  Genetic Position: Chr17, 12.39 cM
Alliance:	E4f1tm1.2Melo page

Germline Transmission:	Earliest citation of germline transmission: J:228251
Parent Cell Line:	G4 (ES Cell)
Strain of Origin:	(129S6/SvEvTac x C57BL/6NCrl)F1

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 14. Cre-mediated recombination removed the selection cassette and exons 2 through 14. (J:228251)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any E4f1 Mutation:	38 strains or lines available

Original:	J:228251 Grote D, et al., E4F1 is a master regulator of CHK1-mediated functions. Cell Rep. 2015 Apr 14;11(2):210-9
All:	1 reference(s)