Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | References

Symbol:	Tg(Pdx1-cre)1Herr
Name:	transgene insertion 1, Pedro Luis Herrera
MGI ID:	MGI:2387562
Synonyms:	Pdx1Late-Cre, PDX1Pr-Cre
Transgene:	Tg(Pdx1-cre)1Herr  Location: unknown
Alliance:	Tg(Pdx1-cre)1Herr page

Strain of Origin:

(C57BL/6J x CBA/J)F2

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Pdx1-cre)1Herr expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Pdx1   Mutation details: The 4.5 kb region containing Pdx1 regulatory sequences was used to drive expression of a cre recombinase constructed modified with a nuclear localization signal upstream of a human hGH minigene. The Pdx1 promoter drives expression in the pancreas. Mosaic cre expression is first observed in the pancreatic epithelium at E11.5. Expression continues to be mosaic at E12.5. (J:78865, J:108521)

Activity:	Tissue activity of this recombinase allele
Driver:	Pdx1 (species not specified) Summary of all recombinase alleles driven by Pdx1. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:78865 Herrera PL, Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages. Development. 2000 Jun;127(11):2317-22
All:	41 reference(s)