About   Help   FAQ
Il15Defm
Chemically induced Allele Detail
Summary
Symbol: Il15Defm
Name: interleukin 15; deficient memory
MGI ID: MGI:5749834
Synonyms: DM, Il-15deltaE7, P191
Gene: Il15  Location: Chr8:83058261-83129851 bp, - strand  Genetic Position: Chr8, 39.33 cM
Alliance: Il15Defm page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU induced a C to T mutation (third position of the boxed triplet codon) in exon 7. This mutation creates a new splice site resulting in expression of an mRNA lacking a 48 bp region of the 5' end of exon 7. The mutant protein lacks the first 16 amino acids of exon 7. (J:220593)
Inheritance:    Not Specified
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Il15 Mutation:  43 strains or lines available
References
Original:  J:220593 Lee TL, et al., An Alternatively Spliced IL-15 Isoform Modulates Abrasion-Induced Keratinocyte Activation. J Invest Dermatol. 2015 May;135(5):1329-37
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/19/2024
MGI 6.23
The Jackson Laboratory