Il15Defm
Chemically induced Allele Detail
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Symbol: |
Il15Defm |
Name: |
interleukin 15; deficient memory |
MGI ID: |
MGI:5749834 |
Synonyms: |
DM, Il-15deltaE7, P191 |
Gene: |
Il15 Location: Chr8:83058261-83129851 bp, - strand Genetic Position: Chr8, 39.33 cM
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Alliance: |
Il15Defm page
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Strain of Origin: |
Not Specified
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Allele Type: |
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Chemically induced (ENU) |
Mutation: |
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Single point mutation
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Mutation details: ENU induced a C to T mutation (third position of the boxed triplet codon) in exon 7. This mutation creates a new splice site resulting in expression of an mRNA lacking a 48 bp region of the 5' end of exon 7. The mutant protein lacks the first 16 amino acids of exon 7.
(J:220593)
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Inheritance: |
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Not Specified |
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Il15 Mutation: |
43 strains or lines available
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Original: |
J:220593 Lee TL, et al., An Alternatively Spliced IL-15 Isoform Modulates Abrasion-Induced Keratinocyte Activation. J Invest Dermatol. 2015 May;135(5):1329-37 |
All: |
1 reference(s) |
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