Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Daotm1Ttsu
Name:	D-amino acid oxidase; targeted mutation 1, Takashi Tsukamoto
MGI ID:	MGI:5708529
Gene:	Dao  Location: Chr5:114141764-114163743 bp, + strand  Genetic Position: Chr5, 55.93 cM
Alliance:	Daotm1Ttsu page

Germline Transmission:	Earliest citation of germline transmission: J:228710
Parent Cell Line:	Other (see notes) (ES Cell)
Strain of Origin:	129S6/SvEvTac

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin resistance cassette replaced 1957 bp, encompassing exon 7 and 8. Western blot analysis confirmed the absence of protein expression in the cerebellum. (J:228602, J:228710)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dao Mutation:	26 strains or lines available

Original:	J:228710 Rais R, et al., Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice. Drug Metab Dispos. 2012 Nov;40(11):2067-73
All:	4 reference(s)