Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dmrtb1tm1.1Zark
Name:	DMRT-like family B with proline-rich C-terminal, 1; targeted mutation 1.1, David Zarkower
MGI ID:	MGI:5705340
Synonyms:	Dmrt6-
Gene:	Dmrtb1  Location: Chr4:107533487-107541427 bp, - strand  Genetic Position: Chr4, 50.18 cM, cytoband C7
Alliance:	Dmrtb1tm1.1Zark page

Germline Transmission:	Earliest citation of germline transmission: J:217504
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A loxP site was inserted upstream of exon 1 and an FRT flanked pgk-neo cassette and loxP site were inserted downstream of exon 1 via homologous recombination. Cre mediated recombination removed exon 1 and the pgk-neo cassette. (J:217504)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Dmrtb1 Mutation:	16 strains or lines available

Original:	J:217504 Zhang T, et al., The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis. Development. 2014 Oct;141(19):3662-71
All:	1 reference(s)