Tnfrsf17tm1Msc
Targeted Allele Detail
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| Symbol: |
Tnfrsf17tm1Msc |
| Name: |
tumor necrosis factor receptor superfamily, member 17; targeted mutation 1, Martin L Scott |
| MGI ID: |
MGI:2387427 |
| Synonyms: |
BCMA- |
| Gene: |
Tnfrsf17 Location: Chr16:11131676-11137938 bp, + strand Genetic Position: Chr16, 6.42 cM, cytoband B3
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| Alliance: |
Tnfrsf17tm1Msc page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:71681
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| Parent Cell Line: |
D3 (ES Cell)
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| Strain of Origin: |
129S2/SvPas
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A region of the gene containing the translation initiation codon and 1.3 kb of downstream sequences were replaced with a human CD2 reporter gene fused to a neomycin resistance cassette. The mutation deletes the first 87 residues, which includes a putative transmembrane domain. Northern blot analysis of spleen RNA using probes to the deleted region did not detect gene transcript in homozygous mutant animals.
(J:71681)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Tnfrsf17 Mutation: |
20 strains or lines available
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| Original: |
J:71681 Schiemann B, et al., An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science. 2001 Sep 14;293(5537):2111-4 |
| All: |
3 reference(s) |
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Analysis Tools
