Stk11tm2Tpm
Targeted Allele Detail
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Symbol: |
Stk11tm2Tpm |
Name: |
serine/threonine kinase 11; targeted mutation 2, Tomi P Makela |
MGI ID: |
MGI:2387004 |
Gene: |
Stk11 Location: Chr10:79951637-79966516 bp, + strand Genetic Position: Chr10, 39.72 cM
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Alliance: |
Stk11tm2Tpm page
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Germline Transmission: |
Earliest citation of germline transmission:
J:70892
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: Sequence encoding exons 2 through 7 were flanked by single loxP sites inserted into introns 1 and 7 in inverse orientations. A neo cassette was also inserted immediately downstream of the intron 7 loxP site. Mice carrying this allele were bred with transgenic mice expressing cre recombinase to generate Stk11tm2.1Tpm.
(J:70892)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Stk11 Mutation: |
34 strains or lines available
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Original: |
J:70892 Ylikorkala A, et al., Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice. Science. 2001 Aug 17;293(5533):1323-6 |
All: |
1 reference(s) |
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