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Myod1tm1.1(cre/ERT2)Lepr
Targeted Allele Detail
Summary
Symbol: Myod1tm1.1(cre/ERT2)Lepr
Name: myogenic differentiation 1; targeted mutation 1.1, Christoph Lepper
MGI ID: MGI:5620011
Synonyms: MyoD1CE
Gene: Myod1  Location: Chr7:46025898-46028516 bp, + strand  Genetic Position: Chr7, 30.03 cM
Alliance: Myod1tm1.1(cre/ERT2)Lepr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:210509
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6 x 129
Mutation
description
Allele Type:    Targeted (Inducible, Null/knockout, Recombinase)
Inducer:    tamoxifen
Mutations:    Insertion, Intragenic deletion
 
Myod1tm1.1(cre/ERT2)Lepr expression driven by 1 gene
 
Mutation detailsA rabbit beta-globin intron, cre/ERT2 fusion gene, SV40 late polyadenylation signal and FRT-flanked neomycin cassette replaced the coding sequence in exon 1. Flp-mediated recombination removed the selection cassette. (J:210509)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myod1 (mouse)
Summary of all recombinase alleles driven by Myod1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Myod1 Mutation:  23 strains or lines available
References
Original:  J:210509 Southard S, et al., A series of Cre-ER(T2) drivers for manipulation of the skeletal muscle lineage. Genesis. 2014 Aug;52(8):759-70
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory