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Atoh1tm2(Ptf1a)Mhos
Targeted Allele Detail
Summary
Symbol: Atoh1tm2(Ptf1a)Mhos
Name: atonal bHLH transcription factor 1; targeted mutation 2, Mikio Hoshino
MGI ID: MGI:5617550
Synonyms: Atoh1Ptf1a
Gene: Atoh1  Location: Chr6:64706109-64708229 bp, + strand  Genetic Position: Chr6, 30.03 cM
Alliance: Atoh1tm2(Ptf1a)Mhos page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:210443
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence, Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Atoh1tm2(Ptf1a)Mhos expresses 1 gene
    The open reading frame of the gene was replaced with a cDNA for Ptf1a and a floxed pgk-neo cassette. (J:210443)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Atoh1 Mutation:  36 strains or lines available
References
Original:  J:210443 Yamada M, et al., Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons. J Neurosci. 2014 Apr 2;34(14):4786-800
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory