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Ptf1atm1.1(Atoh1)Mhos
Targeted Allele Detail
Nomenclature
Symbol: Ptf1atm1.1(Atoh1)Mhos
Name: pancreas specific transcription factor, 1a; targeted mutation 1.1, Mikio Hoshino
MGI ID: MGI:5617549
Synonyms: Ptf1aAtoh1
Gene: Ptf1a  Location: Chr2:19445663-19447501 bp, + strand  Genetic Position: Chr2, 13.37 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:210443
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence, Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Ptf1atm1.1(Atoh1)Mhos expresses 1 gene
 
Mutation detailsThe open reading frame of the gene was replaced with a cDNA for Atoh1 and a floxed pgk-neo cassette. Cre mediated recombination removed the neo cassette. (J:210443)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptf1a Mutation:  18 strains or lines available
References
Original:  J:210443 Yamada M, et al., Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons. J Neurosci. 2014 Apr 2;34(14):4786-800
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/05/2021
MGI 6.16
The Jackson Laboratory