Summary | Mutation origin | Mutation description | Find Mice (IMSR) | References

Symbol:	Mirc10tm1Mtm
Name:	microRNA cluster 10, including Mir15b through Mir16-2; targeted mutation 1, Michael McManus
MGI ID:	MGI:5614202
Synonyms:	miR-15b/ miR-16-2
Gene:	Mirc10  Location: Chr3:68917105-68917329 bp  Genetic Position: Chr3, Syntenic

Germline Transmission:	Earliest citation of germline transmission: J:181752
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A targeting vector was designed to insert an FRT site followed by a lacZ gene, a loxP site, a neomycin cassette, an FRT site and a loxP site (FRT-lacZ-loxP-Neo-FRT-loxP) upstream of the microRNA stem loop and one loxP site immediately downstream of the microRNA stem loop. (J:181752)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Mirc10 Mutation:	4 strains or lines available

Original:	J:181752 Park CY, et al., A resource for the conditional ablation of microRNAs in the mouse. Cell Rep. 2012;1(4):385-91
All:	3 reference(s)