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Mef2ctm1.1Wtp
Targeted Allele Detail
Summary
Symbol: Mef2ctm1.1Wtp
Name: myocyte enhancer factor 2C; targeted mutation 1.1, William T Pu
MGI ID: MGI:5606040
Synonyms: CVDC/B2B program mutation, Mef2c-flbio
Gene: Mef2c  Location: Chr13:83652153-83815199 bp, + strand  Genetic Position: Chr13, 43.68 cM
Alliance: Mef2ctm1.1Wtp page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:185868
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Project Collection: B2B/CvDC
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a FLAG/bio epitope tag and a frt-flanked neomycin resistance (neo) cassette at the endogenous Mef2c stop codon and upstream of the 3' UTR. FLP mediated recombination removed the FRT-flanked neo cassette. (J:185868)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mef2c Mutation:  33 strains or lines available
References
Original:  J:185868 Schramm C, Information about alleles developed by members of the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program. MGI Direct Data Submission. 2012;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory