Rr320tm1Mkg
Targeted Allele Detail
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| Symbol: |
Rr320tm1Mkg |
| Name: |
regulatory region 320; targeted mutation 1, Mark Groudine |
| MGI ID: |
MGI:2386945 |
| Synonyms: |
delta145, Hbb-artm1Mkg |
| Gene: |
Rr320 Location: Chr7:103501973-103526752 bp, + strand Genetic Position: Chr7, Syntenic
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| Alliance: |
Rr320tm1Mkg page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:60714
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
129
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| Allele Type: |
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Targeted (Modified regulatory region, Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The 5' DNase hypersensitive site 1 (HS1) of the gene was replaced with a loxP site flanked neomycin resistance gene cassette and HS 4-6 were replaced with a loxP site flanked hygromycin resistance gene cassette and a partial neo cassette via homologous recombination.
(J:60714)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Rr320 Mutation: |
0 strains or lines available
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| Original: |
J:60714 Bender MA, et al., Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control region. Mol Cell. 2000 Feb;5(2):387-93 |
| All: |
1 reference(s) |
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Analysis Tools
