Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Serpina1atm1Amgh
Name:	serine (or cysteine) peptidase inhibitor, clade A, member 1A; targeted mutation 1, A McGarry Houghton
MGI ID:	MGI:5566806
Gene:	Serpina1a  Location: Chr12:103819848-103829821 bp, - strand  Genetic Position: Chr12, 52.98 cM
Alliance:	Serpina1atm1Amgh page

Germline Transmission:	Earliest citation of germline transmission: J:208746
Parent Cell Line:	RW-4 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion     A GFP gene and floxed neomycin resistance cassette were inserted into exon 2. (J:208746)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Serpina1a Mutation:	21 strains or lines available

Original:	J:208746 Wang D, et al., Deletion of Serpina1a, a murine alpha1-antitrypsin ortholog, results in embryonic lethality. Exp Lung Res. 2011 Jun;37(5):291-300
All:	1 reference(s)