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Hprt1tm3(Ar-luc)Geno
Targeted Allele Detail
Summary
Symbol: Hprt1tm3(Ar-luc)Geno
Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 3, Genoway
MGI ID: MGI:5555881
Synonyms: ARE-Luc
Gene: Hprt1  Location: ChrX:52077014-52110536 bp, + strand  Genetic Position: ChrX, 29.31 cM, cytoband A6
Alliance: Hprt1tm3(Ar-luc)Geno page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:205903
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Inducible, Reporter)
Inducer:    androgen
Mutation:    Insertion
 
Mutation detailsThe targeting construct introduced into the locus an activated endogenous Ar promoter (SC1.2-ARE) driving androgen-mediated luciferase activity (ARE-Luc) and reconstituted the Hprt gene. (J:205903)
Generation of the Hprt1tm3(Ar-luc)Geno allele
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hprt1 Mutation:  1273 strains or lines available
References
Original:  J:205903 Dart DA, et al., Visualising androgen receptor activity in male and female mice. PLoS One. 2013;8(8):e71694
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory