Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ccr2tm1.1(CCR2)Rodb
Name:	C-C motif chemokine receptor 2; targeted mutation 1.1, Robert D Berahovich
MGI ID:	MGI:5552734
Synonyms:	hCCR2 KI
Gene:	Ccr2  Location: Chr9:123901987-123913594 bp, + strand  Genetic Position: Chr9, 75.05 cM, cytoband F
Alliance:	Ccr2tm1.1(CCR2)Rodb page

Germline Transmission:	Earliest citation of germline transmission: J:203000
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted Mutations:    Insertion, Intragenic deletion   Mutation details: The mouse coding region was replaced with the corresponding human coding sequence. Cre-mediated recombination removed the neomycin resistance cassette. (J:203000)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccr2 Mutation:	40 strains or lines available

Original:	J:203000 Sullivan T, et al., CCR2 antagonist CCX140-B provides renal and glycemic benefits in diabetic transgenic human CCR2 knockin mice. Am J Physiol Renal Physiol. 2013 Nov;305(9):F1288-97
All:	2 reference(s)