Fusem2Rkuhn
Endonuclease-mediated Allele Detail
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| Symbol: |
Fusem2Rkuhn |
| Name: |
fused in sarcoma; endonuclease-mediated mutation 2, Ralf Kuhn |
| MGI ID: |
MGI:5551890 |
| Synonyms: |
FusP517L |
| Gene: |
Fus Location: Chr7:127565276-127581204 bp, + strand Genetic Position: Chr7, 69.87 cM
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| Alliance: |
Fusem2Rkuhn page
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| Strain of Origin: |
(FVB/N x D2B6F1)F1
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| Allele Type: |
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Endonuclease-mediated |
| Mutation: |
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Nucleotide substitutions
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Mutation details: TALEN targeting of exon 15 for homologous recombination with a synthetic oligodeoxynucleotide induced a point mutation (C to T) that results in the amino acid substitution of leucine for phenylalanine at position 517 (P517L). Founder F36 exhibit the intended point mutation and an additional nucleotide substitution G to A in the TALEN-Fus15B targeting sequence.
(J:201579)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Fus Mutation: |
39 strains or lines available
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| Original: |
J:201579 Panda SK, et al., Highly efficient targeted mutagenesis in mice using TALENs. Genetics. 2013 Nov;195(3):703-13 |
| All: |
1 reference(s) |
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Analysis Tools
