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Tbx20tm1.2Rph
Targeted Allele Detail
Summary
Symbol: Tbx20tm1.2Rph
Name: T-box 20; targeted mutation 1.2, Richard P Harvey
MGI ID: MGI:5551507
Synonyms: Tbx20f
Gene: Tbx20  Location: Chr9:24632108-24685580 bp, - strand  Genetic Position: Chr9, 10.25 cM
Alliance: Tbx20tm1.2Rph page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a single loxP site 5' of the initiation codon in exon 1 and a loxP-flanked neomycin resistance (neo) cassette followed by a beta-galactosidase (lacZ) sequence downstream of exon 3. Mutant mice were bred to mice carrying Tg(rtetR-tetO-cre)40Mhz. Progeny were selected to retain loxP sites in introns 1 and 3, but an excised neomycin selection cassette. (J:98489, J:101977)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tbx20 Mutation:  34 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory